科研成果
生命学院代表性论文
Establishment of chromatin architecture interplays with embryo hypertranscription
Yu, Guang; Xu, Kai; Xia, Weikun; Zhang, Ke; Xu, Qianhua; Li, Lijia; Lin, Zili; Liu, Ling; Liu, Bofeng; Du, Zhenhai; Chen, Xia; Fan, Qiang; Lai, Fangnong; Wang, Wenying; Wang, Lijuan; Kong, Feng; Wang, Chao; Dai, Haiqiang; Wang, Huili; Xie, Wei
Nature
Remodelling autoactive NLRs for broad-spectrum immunity in plants
Wang, Junzhu; Chen, Tianyuan; Zhang, Zhendong; Song, Mengjie; Shen, Tianxin; Wang, Xin; Zheng, Xiyin; Wang, Yan; Song, Ke; Ge, Xiaoyang; Xu, Kai; Qi, Tiancong; Li, Fuguang; Hong, Yiguo; Liu, Yule
Nature
Subnucleosome preference of human chromatin remodeller SMARCAD1
Hu, Pengjing; Sun, Jingxi; Sun, Hongyao; Chen, Kangjing; Sia, Youyang; Xia, Xian; Xi, Qiaoran; Chen, Zhucheng
Nature
Structural insights into chromatin remodeling by ISWI during active ATP hydrolysis
Sia, Youyang; Pan, Han; Chen, Kangjing; Chen, Zhucheng
Science
Composite transposons with bivalent histone marks function as RNA-dependent enhancers in cell fate regulation
Zhou, Ziqiang; Zhu, Shicong; Hong, Yaqiang; Jin, Guangpu; Ma, Rui; Lin, Fan; Zhang, Yiyang; Lee, Hsiang-Ying; Liu, Nian
Cell
Integrating reproductive states and social cues in the control of sociosexual behaviors
Wang, Yuping; Song, Xinli; Chen, Xiangmao; Zhou, Ying; Ma, Jihao; Zhang, Fang; Wei, Liqiang; Qi, Guoxu; Yadav, Nakul; Miao, Benjie; Yan, Yiming; Yuan, Guohua; Mi, Da; Rajasethupathy, Priyamvada; Ibanez-Tallon, Ines; Jia, Xiaoxuan; Heintz, Nathaniel; Li, Kun
Cell
CRISPR live-cell imaging reveals chromatin dynamics and enhancer interactions at multiple non-repetitive loci
Liu, Meishuo; Huang, Keyun; Zhang, Jie; Li, Qingyang; Wang, Xinming; Gu, Buming; Tang, Hao; Du, Zhenhai; Hu, Liangjun; Qi, Shutao; Ma, Yu; Yu, Hongtao; Xie, Wei; Fang, Xianyang; Wang, Haifeng
Nature Biotechnology
A famsin-glucagon axis mediates glucose homeostasis
Long, Aijun; Wang, Yazhuo; Guo, Yihua; Hong, Jie; Ning, Guang; Meng, Zhuoxian; Wang, Jiqiu; Wang, Yiguo
Cell Metabolism
Maternal factor OTX2 regulates human embryonic genome activation and early development
Wang, Qiuyan; Zhang, Chuanxin; Dang, Yanna; Sun, Jiaqi; Zou, Zhuoning; Li, Cheng; Ma, Shuiying; Li, Zongyu; Liu, Hui; Ma, Xiaonan; Yang, Zhen; Wang, Lijuan; Wu, Keliang; Chen, Zi-Jiang; Xie, Wei; Zhao, Han
Nature Genetics
ETV7 limits the antiviral and antitumor efficacy of CD8+ T cells by diverting their fate toward exhaustion
Cheng, Jie; Xiao, Yifeng; Peng, Ting; Zhang, Zijian; Qin, You; Wang, Yuqian; Shi, Jiangzhou; Yan, Jinxin; Zhao, Zihao; Zheng, Liangtao; He, Zhijun; Wang, Jianwei; Zhang, Zemin; Li, Cheng; Zhu, Haichuan; Jiang, Peng
Nature Cancer
A thermosensor FUST1 primes heat-induced stress granule formation via biomolecular condensation in Arabidopsis
Geng, Pan; Li, Changxuan; Quan, Xuebo; Peng, Jiaxuan; Yao, Zhiying; Wang, Yunhe; Yang, Ming; Wang, Yanning; Jin, Yunfan; Xiong, Yan; Liu, Hongtao; Qi, Yijun; Yang, Peiguo; Huang, Kai; Fang, Xiaofeng
Cell Research
Improving diffusion-based protein backbone generation with global-geometry-aware latent encoding
Zhang, Yuyang; Liu, Yuhang; Ma, Zinnia; Li, Min; Xu, Chunfu; Gong, Haipeng
Nature Machine Intelligence
Cellular Feimin enhances exercise performance by suppressing muscle thermogenesis
Peng, Ying; Jia, Liangjie; Hu, Xiao; Shi, Xiaoliu; Fang, Xinlei; Qiu, Yifu; Gan, Zhenji; Wang, Yiguo
Nature Metabolism
A feeding-induced myokine modulates glucose homeostasis
Shi, Xiaoliu; Hu, Xiao; Fang, Xinlei; Jia, Liangjie; Wei, Fangchao; Peng, Ying; Liu, Menghao; Gao, Aibo; Zhao, Ke; Chen, Fengyi; Hu, Xiaoli; Hong, Jie; Ning, Guang; Song, Yongfeng; Wang, Jiqiu; Wang, Yiguo
Nature Metabolism
EZHIP restricts noncanonical PRC2 binding and regulates H3K27me3 intergenerational inheritance and reprogramming
Zeng, Yitian; Kong, Feng; Xu, Zihan; Lu, Xukun; Li, Qian; Liu, Bofeng; Liu, Shu; Dong, Lijun; Liu, Ling; Wang, Wenying; Zhu, Bing; Xie, Wei
Cell Stem Cell
The migrasome, an organelle for cell-cell communication
Jiang, Dong; He, Jinzhao; Yu, Li
Trends in Cell Biology
The emerging roles of the urea cycle in tumor microenvironment and therapies
Zhou, Jiawen; Sun, Xuan; Jiang, Peng
Trends in Cancer
Advances in understanding LINE-1 regulation and function in the human genome
Li, Xiufeng; Liu, Nian
Trends in Genetics
An orthogonal transcription mutation system generating all transition mutations for accelerated protein evolution in vivo
Shao, Mingwei; Zhang, Zhongnan; Jin, Xiaofan; Ding, Jun; Chen, Guo-Qiang
Nature Communications
Solid-like condensation of MORF8 inhibits RNA editing under heat stress in Arabidopsis
Wu, Jie; Wang, Yue; Chen, Haodong; Xu, Tongda; Yang, Wenqiang; Fang, Xiaofeng
Nature Communications
MPicker: visualizing and picking membrane proteins for cryo-electron tomography
Yan, Xiaofeng; Li, Shudong; Huang, Weilin; Wang, Hao; Zhao, Tianfang; Huang, Mingtao; Zhou, Niyun; Shen, Yuan; Li, Xueming
Nature Communications
Adipose tissue-derived PRXL2A suppresses hepatic lipogenesis in a study with male mice
Li, Zhiyuan; Tian, Zheng; Shi, Xiaoliu; Long, Aijun; Wang, Yazhuo; Yang, Yan; Wang, Yaqi; Zhang, Jingjing; Wang, Yiguo
Nature Communications
Automated design of scaffold-free DNA wireframe nanostructures
Wang, Wen; Mohammed, Abdulmelik; Chen, Rong; Elonen, Antti; Chen, Silian; Tian, Mengfan; Yang, Junhao; Xiang, Ye; Orponen, Pekka; Wei, Bryan
Nature Communications
An oncohistone-driven H3.3K27M/CREB5/ID1 axis maintains the stemness and malignancy of diffuse intrinsic pontine glioma
Zhou, Wei; Xu, Cheng; Yang, Shuangrui; Li, Haocheng; Pan, Changcun; Jiang, Zhuang; Xie, Luyang; Li, Xiaohan; Qiao, Huimin; Mi, Da; Tang, Yujie; Zhang, Liwei; Xi, Qiaoran
Nature Communications
Glutathione triggers leaf-to-leaf, calcium-based plant defense signaling
Li, Rui; Yang, Yongfang; Lou, Hao; Wang, Weicheng; Du, Ran; Chen, Haidong; Du, Xiaoxi; Hu, Shuai; Wang, Guo-Liang; Yan, Jianbin; Shan, Xiaoyi; Xie, Daoxin
Nature Communications
An intermediate open structure reveals the gating transition of the mechanically activated PIEZO1 channel
Liu, Sijia; Yang, Xuzhong; Chen, Xudong; Zhang, Xiaochun; Jiang, Jinghui; Yuan, Jingyi; Liu, Wenhao; Wang, Li; Zhou, Heng; Wu, Kun; Tian, Boxue; Li, Xueming; Xiao, Bailong
Neuron
Reconstructing a new hippocampal engram for systems reconsolidation and remote memory updating
Lei, Bo; Kang, Bilin; Hao, Yuejun; Yang, Haoyu; Zhong, Zihan; Zhai, Zihan; Zhong, Yi
Neuron
Pathogen-induced condensation of the guard cell RNA-binding protein SAIR1 fine-tunes translation for immunity
Yu, Qiangsheng; Wu, Jie; Jin, Yunfan; Song, Tianxue; Wang, Wenrui; Zeng, Yuejuan; Huang, Huang; Deng, Haiteng; Wang, Wei; Xie, Jianghui; Lu, Zhi John; Fang, Xiaofeng; Song, Susheng; Qi, Tiancong
Nature Plants
H3K36 methylation stamps transcription resistive to preserve development in plants
Yao, Yao; Zhou, Jincong; Wang, Jiacheng; Lei, Xue; Jiang, Anjie; Sun, Qianwen
Nature Plants
Biosynthesis of poly(δ-valerolactone) (PVL) by Halomonas bluephagenesis
Wang, Jiale; Yan, Xu; Zheng, Shuang; Wen, Rou; Chen, Yiling; Yang, Weinan; Sheng, Junting; Wu, Qiong; Wu, Fuqing; Chen, Guo-Qiang
Chemical Engineering Journal
Production of polyhydroxyalkanoate from acetate by metabolically engineered Halomonas bluephagenesis
Ji, Mengke; Yang, Fang; Zhang, Zhongnan; Wang, Huan; Gao, Te; Fan, Weihua; Gao, Yixin; Zhang, Yaoyao; Wang, Jinghui; Wu, Fuqing; Chen, Guo-Qiang
Chemical Engineering Journal
Structural basis of endo-siRNA processing by Drosophila Dicer-2 and Loqs-PD
Cao, Na; Wang, Jia; Deng, Ting; Fan, Boming; Su, Shichen; Ma, Jinbiao; Wang, Hong-Wei
Nucleic Acids Research
Exploring biotechnology for plastic recycling, degradation and upcycling for a sustainable future
Liu, Xu; Park, Helen; Ackermann, Yannic Sebastian; Averous, Luc; Ballerstedt, Hendrik; Besenmatter, Werner; Blazquez, Blas; Bornscheuer, Uwe T.; Branson, Yannick; Casey, William; de Lorenzo, Victor; Dong, Weiliang; Floehr, Tilman; Godoy, Manuel S.; Ji, Yu; Jupke, Andreas; Klankermayer, Juergen; San Leon, David; Liu, Luo; Liu, Xianrui; Liu, Yizhi; Manoli, Maria T.; Martinez-Garcia, Esteban; Naranciz, Tanja; Nogales, Juan; O'Connor, Kevin; Osterthun, Ole; Perrin, Remi; Prieto, M. Auxiliadora; Pollet, Eric; Sarbu, Alexandru; Schwaneberg, Ulrich; Su, Haijia; Tang, Zequn; Tiso, Till; Wang, Zishuai; Wei, Ren; Welsing, Gina; Wierckx, Nick; Wolter, Birger; Xiao, Gang; Xing, Jianmin; Zhao, Yilin; Zhou, Jie; Tan, Tianwei; Blank, Lars M.; Jiang, Min; Chen, Guo-Qiang
Biotechnology Advances
Molecular and neural basis of vomiting behavior in Drosophila melanogaster
Shi, Yanyan; Jia, Yinjun; Zhang, Wei
Science Advances
Glycerol-Assisted DNA Self-Assembly at Low Temperatures
Sun, Zhengyang; Wang, Wen; Wei, Bryan
Small
H2A.Z is essential for oocyte maturation and fertility in female mouse
Xu, Qianhua; Huang, Chunyi; Ming, Jia; Lu, Xukun; Liu, Ling; Du, Zhenhai; Chen, Zhen; Na, Jie; Li, Guohong; Xiang, Yunlong; Zhang, Yu; Xie, Wei
Nature Structural & Molecular Biology
