科研成果
生命学院代表性论文
Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon
Deng, Pujuan; Tan, Shun-Qing; Yang, Qi-Yu; Fu, Liangzheng; Wu, Yachao; Zhu, Han-Zhou; Sun, Lei; Bao, Zhangbin; Lin, Yi; Zhang, Qiangfeng Cliff; Wang, Haoyi; Wang, Jia; Liu, Jun-Jie Gogo
Cell
OBOX regulates mouse zygotic genome activation and early development
Ji, Shuyan; Chen, Fengling; Stein, Paula; Wang, Jiacheng; Zhou, Ziming; Wang, Lijuan; Zhao, Qing; Lin, Zili; Liu, Bofeng; Xu, Kai; Lai, Fangnong; Xiong, Zhuqing; Hu, Xiaoyu; Kong, Tianxiang; Kong, Feng; Huang, Bo; Wang, Qiujun; Xu, Qianhua; Fan, Qiang; Liu, Ling; Williams, Carmen J.; Schultz, Richard M.; Xie, Wei
Nature
Molecular basis of methyl-salicylate-mediated plant airborne defence
Gong, Qian; Wang, Yunjing; He, Linfang; Huang, Fan; Zhang, Danfeng; Wang, Yan; Wei, Xiang; Han, Meng; Deng, Haiteng; Luo, Lan; Cui, Feng; Hong, Yiguo; Liu, Yule
Nature
In situ structure of the red algal phycobilisome-PSII-PSI-LHC megacomplex
You, Xin; Zhang, Xing; Cheng, Jing; Xiao, Yanan; Ma, Jianfei; Sun, Shan; Zhang, Xinzheng; Wang, Hong-Wei; Sui, Sen-Fang
Nature
Nuclear export of pre-60S particles through the nuclear pore complex
Li, Zongqiang; Chen, Shuaijiabin; Zhao, Liang; Huang, Guoqiang; Xu, Huiqin; Yang, Xiaoyun; Wang, Peiyi; Gao, Ning; Sui, Sen-Fang
Nature
Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants
Chen, Jiayue; Yu, Renbo; Li, Na; Deng, Zhaoguo; Zhang, Xinxin; Zhao, Yaran; Qu, Chengfu; Yuan, Yanfang; Pan, Zhexian; Zhou, Yangyang; Li, Kunlun; Wang, Jiajun; Chen, Zhiren; Wang, Xiaoyi; Wang, Xiaolian; He, Shu-Nan; Dong, Juan; Deng, Xing Wang; Chen, Haodong
Cell
Circadian clocks are modulated by compartmentalized oscillating translation
Zhuang, Yanrong; Li, Zhiyuan; Xiong, Shiyue; Sun, Chujie; Li, Boya; Wu, Shuangcheng Alivia; Lyu, Jiali; Shi, Xiang; Yang, Liang; Chen, Yutong; Bao, Zhangbin; Li, Xi; Sun, Chuhanwen; Chen, Yuling; Deng, Haiteng; Li, Tingting; Wu, Qingfeng; Qi, Ling; Huang, Yue; Yang, Xuerui; Lin, Yi
Cell
Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos.
Lijia Li,Fangnong Lai,Xiaoyu Hu,Bofeng Liu, Xukun Lu, Zili Lin, Ling Liu, Yunlong Xiang, Tristan Frum, Michael A. Halbisen, Fengling Chen, Qiang Fan, Amy Ralston, and Wei Xie
Science
NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos
Lai, Fangnong; Li, Lijia; Hu, Xiaoyu; Liu, Bofeng; Zhu, Ziqi; Liu, Ling; Fan, Qiang; Tian, Huabin; Xu, Kai; Lu, Xukun; Li, Qing; Feng, Kong; Wang, Lijuan; Lin, Zili; Deng, Hongyu; Li, Jinsong; Xie, Wei
Cell Research
The compact Casπ (Cas12l) 'bracelet' provides a unique structural platform for DNA manipulation
Sun, Ao; Li, Cheng-Ping; Chen, Zhihang; Zhang, Shouyue; Li, Dan-Yuan; Yang, Yun; Li, Long-Qi; Zhao, Yuqian; Wang, Kaichen; Li, Zhaofu; Liu, Jinxia; Liu, Sitong; Wang, Jia; Liu, Jun-Jie Gogo
Cell Research
Famsin, a novel gut-secreted hormone, contributes to metabolic adaptations to fasting via binding to its receptor OLFR796
Long, Aijun; Liu, Yang; Fang, Xinlei; Jia, Liangjie; Li, Zhiyuan; Hu, Jiang; Wu, Shuang; Chen, Chao; Huang, Ping; Wang, Yiguo
Cell Research
A new route for EV biogenesis.
Yu, Li
Cell Research
The phosphatidylinositol (4,5)-bisphosphate-Rab35 axis regulates migrasome formation
Ding, Tianlun; Ji, Jinyao; Zhang, Weiying; Liu, Yuheng; Liu, Boqi; Han, Yiyang; Chen, Chunlai; Yu, Li
Cell Research
Applications of synthetic biology in medical and pharmaceutical fields
Yan, Xu; Liu, Xu; Zhao, Cuihuan; Chen, Guo-Qiang
Signal Transduction And Targeted Therapy
3-Hydroxybutyrate ameliorates insulin resistance by inhibiting PPARγ Ser273 phosphorylation in type 2 diabetic mice
Zhang, Yudian; Li, Zihua; Liu, Xinyi; Chen, Xinyu; Zhang, Shujie; Chen, Yuemeng; Chen, Jiangnan; Chen, Jin; Wu, Fuqing; Chen, Guo-Qiang
Signal Transduction And Targeted Therapy
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease
Ma, Boyuan; Ju, Anji; Zhang, Shaosen; An, Qi; Xu, Siran; Liu, Jie; Yu, Li; Fu, Yan; Luo, Yongzhang
Signal Transduction And Targeted Therapy
Temporospatial inhibition of Erk signaling is required for lymphatic valve formation
Meng, Yaping; Lv, Tong; Zhang, Junfeng; Shen, Weimin; Li, Lifang; Li, Yaqi; Liu, Xin; Lei, Xing; Lin, Xuguang; Xu, Hanfang; Meng, Anming; Jia, Shunji
Signal Transduction And Targeted Therapy
Dioxygenase JID1 mediates the modification of OPDA to regulate jasmonate homeostasis
Yi, Rong; Du, Ran; Wang, Jiaojiao; Yan, Jijun; Chu, Jinfang; Yan, Jianbin; Shan, Xiaoyi; Xie, Daoxin
Cell Discovery
Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+T cells in the tumor microenvironment
Cheng, Jie; Yan, Jinxin; Liu, Ying; Shi, Jiangzhou; Wang, Haoyu; Zhou, Hanyang; Zhou, Yinglin; Zhang, Tongcun; Zhao, Lina; Meng, Xianbin; Gong, Haipeng; Zhang, Xinxiang; Zhu, Haichuan; Jiang, Peng
Cell Metabolism
Large-scale identification of potential phase- separation proteins from plants using a cell-free system
Zhang, Honghong; Peng, Fangyu; He, Chun; Liu, Yan; Deng, Haiteng; Fang, Xiaofeng
Molecular Plant
R-loopAtlas: An integrated R-loop resource from 254 plant species sustained by a deep-learning- based tool
Li, Kuan; Wu, Zhenzhen; Zhou, Jincong; Xu, Wei; Li, Ling; Liu, Chao; Li, Wei; Zhang, Chengjun; Sun, Qianwen
Molecular Plant
Jasmonate perception: Ligand-receptor interaction, regulation, and evolution
Hu, Shuai; Yu, Kaiming; Yan, Jianbin; Shan, Xiaoyi; Xie, Daoxin
Molecular Plant
Phase separation of the nuclear pore complex facilitates selective nuclear transport to regulate plant defense against pathogen and pest invasion
Wang, Jiaojiao; Pei, Gaofeng; Wang, Yupei; Wu, Dewei; Liu, Xiaokang; Li, Gaoming; He, Jianfang; Zhang, Xiaolin; Shan, Xiaoyi; Li, Pilong; Xie, Daoxin
Molecular Plant
Custom folding of double-stranded DNA directed by triplex formation
Zhang, Tianqing; Qian, Xinmin; Zeng, Wenwen; Wei, Bryan
Chem
Prolonged 3D culture unlocks black box of primate embryogenesis
Li, Ziyi; Zhou, Fan
Cell Stem Cell
Incorporating neuro-inspired adaptability for continual learning in artificial intelligence
Liyuan Wang;Xingxing Zhang;Qian Li;Mingtian Zhang;Hang Su;Jun Zhu；Yi Zhong
Nature Machine Intelligence
The formation of migrasomes is initiated by the assembly of sphingomyelin synthase 2 foci at the leading edge of migrating cells
Liang, Haisha; Ma, Xinyu; Zhang, Yuanyuan; Liu, Yuheng; Liu, Nan; Zhang, Weiying; Chen, Jianhui; Liu, Boqi; Du, Wanqing; Liu, Xiaohui; Yu, Li
Nature Cell Biology
Sphingomyelin synthase 2 foci determine sites of migrasome formation
Liang, Haisha; Yu, Li
Nature Cell Biology
MFSD12 affects glycosphingolipid metabolism by modulating lysosome homeostasis
Hong, Yun; Tian, Zheng; Jia, Liangjie; Wang, Yiguo
Protein & Cell
Recent progress and challenges in the treatment of spinal cord injury
Tian, Ting; Zhang, Sensen; Yang, Maojun
Protein & Cell
How variable progenitor clones construct a largely invariant neocortex
Shen, Zhongfu, Yang, Jiajun, Zhang, Qiangqiang, Wang, Kuiyu, Hu, Xiaolin, Ma, Jjian, and Shi, Song-Hai.
National Science Review
